Abstract
In vitro assay for cytotoxic activity of Nardostachys jatamansi has been carried out against eight human cancer cell lines from six different tissues via 95 per cent methanolic and aqueous extract at the concentration of 100 μg/ml using Sulphorhodamine blue (SRB) assay. Results revealed that methanolic extract from the stem leaves of N. jatamansi showed highest in vitro cytotoxic effect against four human cancer cell lines (A-549, COLO-205, SW-620, NCI-H322) from lung and colon origin. Based on in vitro data, it is suggested that further in vivo studies as well as identification of effective components from methanolic extract and their exact mechanism of action could be useful in designing new anticancer therapeutic agents.
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