Abstract

In vitro assay for cytotoxic activity of Acacia senegal has been carried out against four human cancer cell lines from four different tissues via aqueous extract at the concentration of 10, 30 and 100 μg/ml using Sulphorhodamine blue (SRB) assay. Results revealed that fruit and seed part of the plant showed remarkable in vitro cytotoxic potential against three human cancer cells of cervical (SiHa), neuroblastoma (IMR-32) and lung (A-549) origin at the concentration of 30 and 100 μg/ml. Based on in vitro data, it is suggested that further in vivo studies as well as identification of effective components could be useful in designing new anti-cancer therapeutic agents from this particular plant.

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