Abstract

BackgroundHighly Infectious Diseases (HIDs) are (i) easily transmissible form person to person; (ii) cause a life-threatening illness with no or few treatment options; and (iii) pose a threat for both personnel and the public. Hence, even suspected HID cases should be managed in specialised facilities minimizing infection risks but allowing state-of-the-art critical care. Consensus statements on the operational management of isolation facilities have been published recently. The study presented was set up to compare the operational management, resources, and technical equipment among European isolation facilities. Due to differences in geography, population density, and national response plans it was hypothesized that adherence to recommendations will vary.Methods and FindingsUntil mid of 2010 the European Network for Highly Infectious Diseases conducted a cross-sectional analysis of isolation facilities in Europe, recruiting 48 isolation facilities in 16 countries. Three checklists were disseminated, assessing 44 items and 148 specific questions. The median feedback rate for specific questions was 97.9% (n = 47/48) (range: n = 7/48 (14.6%) to n = 48/48 (100%). Although all facilities enrolled were nominated specialised facilities' serving countries or regions, their design, equipment and personnel management varied. Eighteen facilities fulfilled the definition of a High Level Isolation Unit'. In contrast, 24 facilities could not operate independently from their co-located hospital, and five could not ensure access to equipment essential for infection control. Data presented are not representative for the EU in general, as only 16/27 (59.3%) of all Member States agreed to participate. Another limitation of this study is the time elapsed between data collection and publication; e.g. in Germany one additional facility opened in the meantime.ConclusionThere are disparities both within and between European countries regarding the design and equipment of isolation facilities. With regard to the International Health Regulations, terminology, capacities and equipment should be standardised.

Highlights

  • The term highly infectious diseases (HID) defines mostly viral and bacterial infections that (i) are transmissible from person to person; (ii) cause a life-threatening clinical illness with no or few treatment options; and (iii) pose a threat for both health care workers and the public, requiring specific infection control measures and public health planning [1]

  • In Europe, HIDs have caused several events within the last decade: SARS affected eight European nations in 2003; Lassa virus has repeatedly been imported to Europe; and Crimean Congo Haemorrhagic Fever virus infections are increasing in several Mediterranean regions, and have been imported to central Europe and the United

  • Setting EuroNHID consists of infectious disease clinicians and public health officers with expertise in the management of HIDs identified via their National Health Authorities

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Summary

Introduction

The term highly infectious diseases (HID) defines mostly viral and bacterial infections that (i) are transmissible from person to person; (ii) cause a life-threatening clinical illness with no or few treatment options; and (iii) pose a threat for both health care workers and the public, requiring specific infection control measures and public health planning [1]. The European Commission has funded projects to enhance early recognition of cases by training front-line health care workers (HCWs) and standardizing diagnostic methodology [10,11,12] Despite such efforts, no pooled data on isolation facilities resources, such as infrastructure design, technical equipment, capacity and access to intensive care, do exist.

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