Abstract

Glucuronic acid polymers were isolated after acid treatment (2 m HCl, 100°C, 4h) of immunochemically active extracellular polysaccharides from various moulds belonging to the order of Mucorales. NMR methods have been used to elucidate their structure. It was found that the polymers, which are mainly composed of β(1–4)-linked d-glucuronic acid, can be considered as characteristic fragments of extracellular polysaccharides of all mucoraceous moulds. However, it is unlikely that the glucuronic acid residues play an important role in the immunodominant part of these polysaccharides since no positive ELISA reaction with these polyuronides was found with antibodies raised against the intact native extracellular polysaccharides.

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