Abstract

Background: Simple and less costly screening tools are needed to combat the rising non-communicable diseases epidemic. This study aimed to evaluate the utility of The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for prediabetes, T2D, and metabolic syndrome (MetS) in a population of young adults in urban Mwanza, Tanzania. Methods: A cross-sectional community-based study was conducted among participants aged 18–35 years. The FINDRISC questionnaire was used to collect data and compute the FINDRISC scores for each participant. Socio-demographic, anthropometric, blood glucose, and lipid profiles data were collected accordingly. Results: A total of 259 participants were recruited into the study. The median age was 21 years (IQR 19–27), and more than half 60.2% (156) were females. In total, 32.8% (85) of the participants had at least a slightly elevated risk of developing T2D in 10 years’ time. Compared to the Oral Glucose Tolerance Test (OGTT), FINDRISC had a sensitivity and specificity of 39.1% and 69.2%, respectively (aROC = 0.5). The FINDRISC score significantly correlated with MetS (p = 0.001). Conclusion: In this study, FINDRISC has shown low sensitivity and specificity in the screening of pre-diabetes/T2D. However, it has potential utility in the screening of MetS in a young-adult population.

Highlights

  • Type 2 diabetes mellitus (T2D) is a chronic disease that is characterized by a long prediabetic state before the development of a full-blown disease [1]

  • Using a community-based cross-sectional design, this study aimed to explore the utility of FINDRISC in predicting current diabetes mellitus and metabolic syndrome (MetS) among the youngadult population in an urban setting of Tanzania

  • More than half of the participants had a low risk of developing diabetes mellitus in 10 years, while 32.8% of the participants had at least slightly elevated to a very high risk of T2D in 10 years (Table 2)

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Summary

Introduction

Type 2 diabetes mellitus (T2D) is a chronic disease that is characterized by a long prediabetic state before the development of a full-blown disease [1]. For individuals diagnosed early during pre-diabetes, it is possible to institute interventions that will halt the development of full-blown T2D [3] Standard diagnostic tests, such as the Oral Glucose Tolerance Test (OGTT) and HbA1c, are expensive and difficult to scale up in a large population, especially in resource-limited settings, such as Tanzania [4]. This study aimed to evaluate the utility of The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for prediabetes, T2D, and metabolic syndrome (MetS) in a population of young adults in urban Mwanza, Tanzania. Conclusion: In this study, FINDRISC has shown low sensitivity and specificity in the screening of pre-diabetes/T2D It has potential utility in the screening of MetS in a young-adult population

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