(Invited) Considerations in the Scale-up of Lab-on-Chip and Microfluidics Products

Abstract

Microfluidics-based products are particularly difficult to transition efficiently from a laboratory concept to a beta product that meets target costs for a consumable. The reasons for this has to do with the complexity of microfluidics products, including the use of multiple manufacturing methods and mixed materials to create complete devices, the integration of reagents and liquids, and the integration of sensors. This presentation will discuss the different manufacturing methods involved in the development of a microfluidic product, and present a road map for the timelines and costs for a model cartridge concept. Of particular interest is to consider the trade-offs in not considering design for manufacture during the later part of the research phase before design lock.This presentation will guide start-ups in asking the right questions and getting the right data to their investors to hit milestones and be on track with a credible cost of goods.