Abstract
Aim: This study evaluates structural changes in the normalized volume ratios of the motor and sensory cortices in Parkinson’s patients and compares these changes with healthy individuals to assess the disease's impact on brain structure. Material and Method: The study included 55 Parkinson’s patients (14 females, 41 males) and 28 control subjects (7 females, 21 males). The volumes of the precentral gyrus, paracentral lobulus, and postcentral gyrus were calculated using the BrainSuite automated segmentation software. Regional gray matter volumes were normalized by dividing them by the intracranial volume, and these normalized values were used for comparisons. Volumetric analyses were conducted on the precentral gyrus, postcentral gyrus, and paracentral lobulus to assess their morphological changes associated with Parkinson's disease. Results: Results: In the left hemisphere, the normalized gray matter volume ratios of the postcentral gyrus were found to be lower in Parkinson’s patients (0.82%±0.09) compared to the control group (0.88%±0.09) (p
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call