Investigation and analysis of human immunodeficiency virus infection status of unpaid blood donors in Binzhou City

Abstract

Objective To analyze the human immunodeficiency virus (HIV) infection status of unpaid blood donors in Binzhou City Shandong Province, and to discuss the development trend of HIV infection rate of Binzhou City's unpaid donors, and thus putting forward corresponding countermeasures. Methods From January 2004 to December 2013, a total of 346 424 unpaid blood donors who donated blood in Binzhou Blood Center were chosen as research objects. Among them, there were 226 215 cases of men blood donors and 120 209 cases of women blood donors. The age was ranged from 18 to 55 years old, and the average age was 32.5 years old. All blood donors met the requirement of the Health Inspection Requirements of Blood Donors. Informed consent was obtained from all blood donors before blood collection, and they all signed in the column of informed consent. In order to guarantee the authenticity of the inspection findings, enzyme-linked immunosorbent assay (ELISA) tests were conducted to test blood samples twice. The results were tested and verified again by testing blood in the same test tube and blood in the blood bag if there was one reagent positive reaction in the first test. It was positive if one of two holes showed positive reaction in two-hole experiment, and then the blood samples were sent to Shandong Center for Disease Control and Prevention for HIV confirmation experiment. HIV positive incidence, patient occupation, educational level, age and gender ratio were analyzed by statistical methods. Results The infection rate of HIV in unpaid blood donors in Binzhou from 2004 to 2013 was 6.35/100 000 which was in low infective trend, but it was in a rising trend year by year. Among all the umpaid blood donors, the infection rate of HIV in peasant and unemployed were much higher than those of other occupations, the lower education level, the higher infection rate of HIV, the infection rate of HIV in unpaid blood donors of ≤ 35 years old was higher than those of > 35 years old, and the infection rate of HIV in male blood donors were higher than that of female blood donors, and all the differences were statistically significant (P<0.05). Conclusions The infection rate of HIV in blood donors has shown a gradual increase during the past few years. Therefore, it is significant and important to take measures to reduce infection rate of HIV by blood transfusion and ensure safety of blood transfusion, such as strengthening HIV screening in blood donors, establishing a blood donor HIV screening computer shielding system, raising level of HIV laboratory testing, popularizing AIDS prevention knowledge and so on. Key words: Blood donors; HIV infections; Screening