Abstract

Covid-19 has killed more than 7 million people in the world so far. With general vaccination in 2021, the severity of deaths decreased significantly, but after 6 months, new types of Covid-19 emerged and deaths incidence increased. Epidemiological studies showed that despite high number of deaths, vaccination has reduced the severity of the disease in population. Many researchers did not suggest injecting third and fourth doses due to antigenic changes of virus, but some countries, such as Iran, have continued vaccination. In America and European countries, it has been suggested that vaccination should continue only for high-risk people. Biological science has not rejected dangerous mutations for this virus and has prepared itself to face mutated species of this virus again. Certainly, vaccination is the most important way to deal with the virus in future; but despite millions of mutations in Covid-19 virus structure, the compatibility of vaccine with new viral antigens is important in order to provide effective vaccines with high efficiency.

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