Abstract
Introduction: Traumatic brain injury (TBI) is characterized as an injury or functional damage to the brain caused by traumatic aggression, and is still considered a public health problem. Objectives: To analyze the epidemiological profile of patients hospitalized due to TBI in the Northeast region of the country. Methodology: This is a descriptive, epidemiological study, from January 2009 to December 2019, with data from DATASUS - Ministry of Health. Results: Between 2009 and 2019 there were 299,001 hospitalizations and 30,257 deaths. With 73,133, a presentation from Bahia the highest number of hospitalizations and Pernambuco the highest number of deaths with 6,903 cases. The male gender had the highest number of hospitalizations (78.9%) and deaths (82.6%). Young adults, between 20 and 39 years old, accounted for 40% of hospitalizations and 37.5% of deaths, possibly due to sociocultural and behavioral characteristics. The highest mortality rate was registered in the elderly (21.5%). There was a predominance of brown race in hospitalizations (84.6%) and in deaths (85.5%). In the eleven-year period, there was an increase of 28% in the number of admissions by the TBI, and an increase of 94.7% in hospital costs. Only the state of Paraíba registered a reduction in hospitalizations and deaths due to TBI in the referred period. Conclusion: There is a general worsening in the region, and it is important to formulate education and health policies to reduce TBI morbidity and mortality in the Northeast region of Brazil.
Highlights
Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack
The present review study aimed to address the mechanisms of action of capsaicin and other chemical inducers in mast cell degranulation and an interaction of nerves and events that happen in the dura mater with the activation of mast cells
Conclusion: the analyzed data indicate that the polymorphisms contributed to the susceptibility to Parkinson’s disease (PD), further studies related to the polymorphisms and their relationship to PD are still needed for more ethnic groups, and early diagnosis is possible
Summary
Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack. Methods: A literature review and an observational, descriptive and transversal data collect on treatment for acute demyelinating polyradiculoneuritis, available at DATASUS from January 2008 to December 2020, and articles available at Scielo and PubMed. Results: There were 7,917 hospitalizations, representing a total expenditure of R$ 9,392,552.04, 2009 being the year with the highest number of hospitalizations (809) and 2017 with the highest amount spent during the period (R$ 967,284.65). Methods: A literature review and an observational, descriptive and transversal data collect on surgical treatment was carried out, available from January 2008 to December 2020 and articles available in Scielo, Lilacs and PubMed. Results: There were 15,148 hospitalizations for surgical procedures for the treatment of chronic subdural hematoma, representing a total expenditure of R$ 45,365,258.21, with 2018 being the year with the highest number of hospitalizations (1,418) and with the highest amount spent during the period (R$ 4,570,334.28). Conclusions: The “Coca-Cola Bottle sign” is a classic sign of Graves’ disease, some signs, such as, unilateral and single orbital musculature involvement, may be suggestive of involvement by other etiologies, suggesting the benefit of an early expanded investigation
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