Invasive Fungal Sinusitis with Intracranial Extension and Fatal Outcome: A Case Report

Abstract

Invasive fungal sinusitis is a morbid condition usually encountered in patients with poor immunity, for instance, diabetics or those with lymphoproliferative disease. We report invasive fungal sinusitis in a young immunocompetent host. This case presents a 21-year-old man with an invasive fungal infection and intracranial extension. The patient initially complained of right-sided weakness, headache, vomiting, and diplopia and was subsequently found to have a significant post-contrast enhancement along the left temporal region, encasing the internal carotid artery (ICA). The patient was started on antifungal therapy, and underwent functional endoscopic sinus surgery (FESS) which revealed growth of Aspergillus on fungal culture. He later developed severe cardiac dysfunction and neurological deterioration, ultimately leading to death. This case highlights the significance of taking into account the importance of fungal sinusitis as a potential cause of neurological symptoms, particularly in younger age groups. Early diagnosis and appropriate management are crucial in preventing potentially fatal complications.