Abstract
Dengue shock syndrome (DSS) is a severe and life-threatening consequence of dengue fever, particularly in endemic places like Karachi, Pakistan. This report presents a case of a 30-year-old female patient with DSS who rapidly developed Multi-Organ Dysfunction Syndrome (MODS) and had a fatal outcome. The patient was presented with thrombocytopenia, petechiae, and a high-grade fever and was diagnosed with a positive NS1 antigen test. Within 48 hours, she developed septic shock, Acute Respiratory Distress Syndrome (ARDS), Disseminated Intravascular Coagulation (DIC), and Acute Kidney Damage (AKI) despite early measures such as fluid resuscitation and vasopressor therapy. The main findings were anemia, coagulopathy, and severe thrombocytopenia. After undergoing rigorous fluid therapy, vasopressors, and intensive care unit care, the patient expired on the sixth day due to refractory shock. This instance highlights how crucial it is to identify DSS early and treat it thoroughly to stop its progression to MODS and fatality.
Published Version
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