Abstract
Zinc Oxide nanoparticles (ZNPs) and CS/Zinc oxide nanocomposites (CS/ZnO NCs) were successfully synthesized by wet chemical method. Formation of ZNPs and the interaction of CS/ZnO NCs were characterized by X-ray diffraction (XRD), Zeta potential, and Transmission Electron Microscopy (TEM) techniques. Thermal stability of the prepared samples was characterized by Thermogravimetric Analysis (TGA). TEM images shows the interaction between the ZNPs and CS polymer and the particles has spherical like structure with average crystallite size of 22 nm and is in good agreement with XRD results. The aim of this study was to investigate the attachment of these nanoparticles with Escherichia coli (E. coli) bacterial outermost cell membrane and their mode of action against these bacterial strains by agar well diffusion method and resazurin dye reduction method. Both the test materials synthesized revealed resistivity against E. coli up to 6 mg/mL.
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