Inter-disciplinary approach to the management of central giant cell lesion- A case report

Abstract

Central giant cell Lesion (CGCL) of the jaw is a relatively uncommon benign lesion of unknown etiology. Essentially a destructive process, the most common treatment is surgical removal; however, alternative therapies (intra-lesional injections of corticosteroids, interferon alpha, and calcitonin) have been used in order to avoid undesirable damage to the jaws and teeth. Clinically along with facial asymmetry, the lesion often results in deranged occlusion that must be treated orthodontically. This case report illustrates sequential management of CGCL with intra-lesional corticosteroids followed by surgical re-contouring along with orthodontic considerations in management of associated malocclusion. Difficulties in handling such cases and projecting the recurrence of CGCL shall also be discussed. Keywords: Central giant cell lesion, Buccal cross-bite, Intra-lesional corticosteroids, Orthodontic treatment.