INTENSITY TRANSFORMATION FOR THE MIXTURE COMPOSITIONS OF THE SOLID LUBRICATING BY LACTIN OF LARGE GRAIN LABA AT 1% EFFECT OF METHACRYLIC ACID

Abstract

An increase in the average life expectancy of a person, the occurrence of pathology of solid teeth tissues, periodontal tissues, leads to progressive loss of teeth. In connection with this, there is a need for dentures. However, many patients (30%) of the prosthesis can not use them, or use them only when eating and speaking.
 In the practice of orthopaedic dentistry, as a monomer for the manufacture of removable denture structures, methyl ether is often used. Some authors mention "prosthetic stomatitis" in 25-69% of the examined patients and consider the cause of their occurrence the presence of an excess of monomer in the bases of prosthetics.
 Administration of 1 % ether methacrylic acid leads to the impaired differentiation of the epithelium and is manifested by the intensified keratinisation, caused by its direct irritating effect on the surface of the rat mucosa. Changes in the lamina propriety are manifested by the hyper hydration of the amorphous substance. Inhibited secretion, when the cytoplasm of glandular cells is densely filled with the secretary granules, is detected in the akin. Products of secretion in the lumens of excretory ducts have heterogeneous optical density.
 The purpose of the work was to determine the transformation of the intensity of labelling components of the mucous membrane of the solid palm of the fucosospecific lectin, the common golden rainbow bark (LABA), under the action of 1% ether of methacrylic acid under experimental hypo salivation.
 The intensity of marking using fucosospecific lection of the golden rain of the usual (LABA) mucous membrane of rigid palate under the conditions of 1% ether action of methacrylic acid is established. On the 14th day of observation, the intensity of binding of horny scalar receptors decreased to a moderate morphologically manifested by hyperkeratosis for a given period of observation. Investigation of the specificity of the binding of the components of the plate itself determined the constant expression of the receptors to αL-fucose from the side of fibroblasts and amplification to moderate-collagen fibres. The morphological signs of hyperhydration are determined in the plate. The expression of receptors on the cells of the granular, spiked, basal and basement membranes remained constant at the level of the weak.
 At the 30th day of observation in the epithelial plate of the glandular zone of the mucous membrane of the rigid palate of the rats, the reaction from the side of the horny scales remained moderate, basal – a constant weak. The amplification of binding of receptors is determined in the spiked and granular layers to moderate. Morphologically, the thickness of the epithelial plate significantly decreased in comparison with the intact group, due to violation of the processes of differentiation by the type of pareceratosis.