Integration of Physiochemical Characterization Techniques in Toxicological Screening of Emerging Contaminants in Food and Environment.

Abstract

The pervasive presence of emerging contaminants in food and the environment poses a grave threat to human health and ecological stability. Addressing this challenge necessitates a comprehensive approach that integrates physiochemical characterization techniques into toxicological screening protocols. This paper provides an extensive review of the methodologies and advancements in the amalgamation of various physiochemical characterization techniques, including chromatography, spectroscopy, and mass spectrometry, in toxicological screening for emerging contaminants. By synergistically employing these techniques, the identification, quantification, and toxicity assessment of contaminants are significantly enhanced, facilitating a thorough understanding of their implications for human health and environmental integrity. Through case studies and empirical evidence, this paper underscores the pivotal role of integrated physiochemical characterization techniques in ensuring the safety of food and the environment. By integrating these physiochemical characterization techniques into toxicological screening workflows, researchers can elucidate the presence of emerging contaminants, assess their bioavailability and bioaccumulation potential, and evaluate their toxicological profiles. Furthermore, the synergistic application of these techniques facilitates the identification of transformation products and metabolites, enhancing our understanding of contaminant fate and behavior in environmental matrices and food systems DOI: https://doi.org/10.52783/tjjpt.v45.i02.6483