Abstract
The development and preliminary evaluation of an integrated microanalytical system based on electrochemical detection and cell positioning is reported here. The chip includes ion-sensitive field effect transistors (ISFET), a single pair of castellated microelectrodes and a reference Ag/AgCl microelectrode. The ISFETs have shown good operating characteristics, with a 52 mV/pH response. Yeast cells and bacteria have been positioned on the gate region of the ISFET sensor using single pair of castellated microelectrodes.
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