Abstract
α-,β- and γ-Cyclodextrins (CyDs) and related derivatives have been investigated for their inhibitory effects on the catalytic activity of dipotassium glycyrrhizinate (GK2) in the hydrolysis of polyoxyethylene(60) hydrogenated castor oil, a non-ionic ester surfactant (HCO-60). The activity of GK2 was found to be completely inhibited in the presence of an equimolar amount of γ-CyD owing to the formation of a 1:1 host–guest complex. β-CyD behaved similarly. However, neither inhibition nor complexation was observed in the case of α-CyD. Circular dichroic spectroscopy, using the absorption at 340 nm due to the enone chromophore of GK2, was found to be a useful means to study the details of inclusion of GK2 by CyDs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 2
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
