Abstract
BACKGROUND: Several clinical, angiographic and ultrasonographic factors have been associated to stent restenosis and target lesion revascularization. As to intravascular ultrasound (IVUS) findings, the minimal stent area (MSA) has been correlated with minimal lumen areas (MLA) in patients treated with bare metal and drug eluting stents. OBJECTIVES: Evaluate MSA values of patients treated with EndeavorTM zotarolimus eluting stents capable of predicting MLA 4 mm2 (4.8 mm2 vs. 6.8 mm2, respectively; P = 0.001). ROC curve analysis identified a post-implant MSA of > 5.7 mm2 as a predictor of MLA > 4 mm2 at six months [area under curve: 0.815; 95% confidence interval (95% CI): 0.680.95; P 5.7 mm2 was associated with MLA > 4 mm2 at the mid-term follow-up. These findings may help achieve the optimal deployment of these stents.
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