Abstract

Influence of prolonged exposure to lipoflavon on fibrinolytic activity in rats

Highlights

  • Система фібринолізу тісно пов’язана з функціональною активністю нирок

  • The research animals were divided into the following groups: 1 – control group, 2 – animals treated by Lipoflavon

  • Urine and blood plasma was evaluated by means of determination of azofibrin lysis combined with evaluation of overall, nonenzymatic and rated enzymatic fibrinolytic activity

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Summary

Materials and methods

The experimental study has been performed on albino laboratory rats. The research animals were divided into the following groups: 1 – control group, 2 – animals treated by Lipoflavon. The medicine was administered intra-abdominally at a dose of 370 mg/kg corresponding to 10 mg/kg of quercetin equivalent. The animals were killed at the 24-th hour, at the 48-th hour, at the 967-th hour and on the 7th day of the experiment. The materials under study were urine, blood plasma, blood serum and kidney homogenates. Urine and blood plasma was evaluated by means of determination of azofibrin lysis combined with evaluation of overall, nonenzymatic and rated enzymatic fibrinolytic activity

Results and discussion
Conclusions
Сумарна Неферментативна Ферментативна
ПЕРЕЛІК ВИКОРИСТАНИХ ДЖЕРЕЛ ІНФОРМАЦІЇ
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