Abstract
Abstract INTRODUCTION THE use of diethylstilbestrol (DES) presently is not permissible in the United States as an aid to increasing body weight gains or improving carcass quality in poultry. However, this compound represents a valuable tool for the study of spontaneous dissecting aneurysm (aortic rupture) in turkeys and other metabolic and physiological changes in the bird. DES implantations have been reported by Krista et al. (1961, 1965), Beall et al. (1963), and Simpson and Harms (1965) to increase the incidence of aortic rupture in turkeys. Krista et al. (1965) and Simpson and Harms (1965) reported a concomitant decrease in blood pressure with an increase in aortic rupture. The mechanism of DES producing an increase in aortic rupture has not been elucidated. As reported by Krista et al. (1965), simultaneous injections of testosterone with DES reduced the incidence of aortic rupture. Simpson et al. (1964) noted that additional dietary sodium chloride enhanced…
Published Version
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