Induction of lung tumours by the action of radiation and urethane.

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IN a recent paper, Foley and Cole1 reported some investigations of the incidence of lung tumours in mice exposed to different doses of X-rays, followed by an injection of urethane. They assumed that the lung tumours are induced by the urethane and that the X-rays have an inhibitory effect on the tumour incidence. On this basis they interpreted their results as showing a dependence of this inhibitory action on radiation dose with a threshold of about 300 rads.