IN VITRO evaluation of probiotic properties and bacteriocinogenic potential of strains of microorganisms L. Acidophilus 13, E. Faecium K-50 and their compositions

Abstract

It is known that the gut microbiota plays a central role in the health and biology of the animal, and is therefore important for scientific research. Microorganisms of the genus Lactobacllus are widespread in nature and are considered representatives of the microflora of the macroorganism of the animal. Lactobacllus acidophilus is widely used as a probiotic, and is known for its immunostimulating effect, it colonizes the intestines of a newborn and accompanies the animal throughout its life. Enterococcus faecium is also used as a probiotic, due to its high antagonistic activity against pathogenic microbiota, and also participates in the formation and maintenance of immunity. The purpose of this study was to evaluate the probiotic component of L. acidophilus 13, E. faecium k-50 in conditions simulating the gastrointestinal tract, to study the bacteriocinogenic potential and antagonistic properties of lactobacilli and enterococci and their composition. In this review, we summarize recent advances in understanding the mechanisms involved in bacterial tolerance to bile, with particular emphasis on research contributions. In addition, the physiological and ecological role of enzymes and their importance for animal health, as well as the function of bile acid as a regulator of metabolism, are discussed. Samples were used in the study.