Abstract
ObjectiveTo identify the antibacterial activity and phytochemical analysis of Catharanthus roseus (C. roseus) and also screening of leaf, stem, flower and root extracts of the plant for its antibacterial activity. MethodsAntibacterial activity of C. roseus was performed with different solvents (ethanol and methanol) against various human pathogens viz., Bacillus subtilis (B. subtilis), Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Salmonella thphi (S. thphi) and Pseudomonas aeuroginosa (P. Aeuroginosa). Preliminary phytochemical analysis was carried with potent ethanolic extract. ResultsThe ethanolic extract showed a maximum zone of inhibition (21.15±1.64 mm) against S. typhi and minimum zone of inhibition (06.24±0.69mm) with ethanolic extract against S. aureus. Further, the methanolic extract observed in maximum (15.61±1.35 mm) against S. typhi and minimum (05.20±0.8 6mm) zone of inhibition against E. coli. In addition to the phytochemical analyses were showed the presence of soluble sugar, reducing sugar, protein, amino acids, lipids, total chlorophyll, phenol and ortho-dihydroxyphenols in the ethanolic extract. ConclusionsThe ethanolic extract of C. roseus can be used as potential antibacterial sources.
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