In silico studies on Urtica dioica as aldose reductase inhibitors

Abstract

Listen

Translate article

Urtica dioica L. is a perennial plant which is commonly known as “stinging nettle.” It is widely distributed throughout the temperate and tropical areas around the world. The genus Urtica is derived from word “uro” which means to burn or “urere” which means to sting. Due to the fact that the plant typically either has male or female blooms, the species name is dioica which means “two households”. Apart from various traditional uses, it is reported for the treatment of diabetes. Owing to the antioxidant potential and presence of flavonoids, here in this research, in silico studies has been performed on U. dioica to establish its target affinity against aldose reductase.