Abstract

The procedures used to determine residues of anitibotics in many types of commodities, raw or processes are based upon the classical cylinder-plate diffusion techniques (1). Perhaps the most comprehensive summary of procedures for antibiotic residues are those described by the FDA (2). In general, this publication is a compendium of sensitive and reproducible methods for assaying antibiotic residues. The purpose of this manuscript is to report on the evaluation of improved procedures for determining oxytetracycline in milk and dairy products, chicken muscle tissue and livers, and eggs. The procedures used are based upon those developed for chlortetracycline in similar materials (3,4,5) and are compared to the procedures listed in the FDA compendium of methods and protocols.

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