Implementing the Good Participatory Practice Guidelines in the Girls Achieve Power Trial in South Africa.

A Kutywayo,S Dyani,N P Naidoo,S Mullick,C S Yah,M Malotana

doi:10.1177/2158244018809149

A Kutywayo, S Dyani + Show 4 more

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https://doi.org/10.1177/2158244018809149

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Abstract

The Good Participatory Practice (GPP) guidelines provide a framework for stakeholder engagement within clinical trials, to ensure a study’s acceptability, feasibility, and improving the overall research quality; however, they have rarely been applied beyond this setting, and no literature exists on its application in adolescent research. A review of the 2011 GPP guidelines was undertaken to identify which 16 GPP topic areas could be applied and adapted for implementing an ecological asset building intervention, that is, the Girls Achieve Power (GAP Year) cluster randomized controlled trial for reducing school dropout and increasing reporting of gender-based violence in Gauteng and Western Cape province in South Africa. The 16 GPP topic areas were adapted and implemented to guide stakeholder engagement for GAP Year. We show the usability and adaptability of the GPP framework for guiding stakeholder engagement in non-clinical trials like GAP Year; however it requires adapting to respond to the unique needs of the beneficiaries.

Highlights

Stakeholder involvement is a key component of ensuring a study’s acceptability, feasibility, enrolment, and outcome assessment as well as the design, implementation, and overall quality of the research (Bate et al, 2016; Modi et al, 2014; National Institute for Health Research, 2015)
Good Participatory Practice (GPP) guidelines note that formative research activities usually constitute the initial phase of stakeholder outreach and engagement to understand the local population and context (UNAIDS & AVAC, 2011)
This involved a recap of the GAP Year trial outcomes and intervention approach, progress to date, and the findings of baseline surveys conducted with learners

Summary

Introduction

International, regional, national, local partners and researchers look to each other for guidance throughout the research life cycle (Mack et al, 2013). Underscoring this participatory approach is a desire to conduct research that is designed, owned, and utilized by the community (Ellen, Wallace, Sawe, & Fisher, 2010). There has been increased advocacy for the involvement and engagement of community stakeholders for clinical trials and health research (Molyneux & Bull, 2013) In response to this global dialogue, AVAC (AIDS Vaccine Advocacy Coalition) and UNAIDS (Joint United Nations Programme on HIV/AIDS) developed the Good Participatory Practice (GPP) guidelines (UNAIDS & AVAC, 2011) which seek to set global standards for stakeholder engagement in biomedical HIV prevention trials.

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