Impact of heliogeophysical factors on the clinical-biochemical indices in pregnant women

Abstract

<p>The influence of heliogeophysical factors on the clinical and biochemical parameters of pregnant women with easy and complicated births was studied. The influence of the events of the current day and the previous solar and geomagnetic activity on clinical and biochemical parameters of pregnant women with normal and complicated births was revealed. 164 pregnant women aged from 17 to 44 years, living in Barnaul, Altai region, were examined. According to the type of delivery two groups of women were identified:1) women with easy birth (46 people), 2) women with complicated birth (118 people). The following indicators were used to estimate the level of solar and geomagnetic activity: the number of sunspots, the number of Wolff, radiation at a wavelength of 10.7 cm, the average daily magnetic field perturbation (A<sub>p</sub>– index), and the local geomagnetic disturbance index (A<sub>k </sub>– index). Pregnant women were examined using the following parameters: the number of erythrocytes, leukocytes, blood platelets, leukocyte count, clotting time, erythrocyte sedimentation rate, prothrombin index, hemoglobin, sugar, fibrinogen, bilirubin (direct, indirect and total), total blood protein, and specific gravity. It has been established that the influence of heliogeophysical factors consists of immediate and delayed reactions with different latent periods: among women with normal births the most significant events are the events of the current day, as well as the 3rd, 6th and 7th days before the examination; among women with difficult births - on the 2nd, 4th, 5th and 7th days. Among heliogeophysical factors the average daily disturbance of the Earth's magnetic field has the greatest influence on clinical and biochemical parameters. 60% of the clinical and biochemical parameters analyzed among pregnant women depend on this factor. Clinical and biochemical indicators are less susceptible to heliogeophysical factors among women with complicated births. The coefficient of determination by the factors of solar activity reaches 25% (direct bilirubin) among them; factors of geomagnetic activity - 31.5% (urine protein), whereas in the group of women with normal births the coefficient of determination is 50% (total bilirubin) and 71% (total bilirubin). According to clinical-biochemical indicators 8 types of correlations were found: 1 type – at low level of solar and geomagnetic activity, 4 types – at medium and 3 types at high level. Linear and nonlinear functional dependencies of the indicators on heliogeophysical factors are revealed for each typological group.</p>