Abstract
There is no doubt that Alzheimer disease (AD) is one of the most deadly and expensive diseases in the world today. It accounts for the majority of patients with dementia. The disease is caused by a combination of environmental and genetic factors, and identifying effective environmental factors can play a significant role in controlling and preventing this disease. Heavy metals (HMs) can be ingested, inhaled, or absorbed through the skin by the human body. As a result of HM accumulation in the body, many organs, including the nervous system, are adversely affected. Accordingly, memory, cognition, and learning functions may be negatively affected. In recent years, there has been considerable interest in the effect of HMs on AD, and several studies have examined how HMs affect brain function and AD. During this study, we will review these studies and examine how HMs may influence AD development. As a result of the limitations of traditional methods in identifying HM toxicity, this study discusses artificial intelligence (AI) and its advantages and limitations as a tool for determining HMs associated with AD.
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