Abstract
The immune-boosting potential of phytochemicals from plant products in Nigeria has gained significant attention in recent years. Phytochemicals are bioactive compounds found in plants that have been shown to possess immunomodulatory properties. Nigeria is a country with rich biodiversity, and its traditional medicine practices rely heavily on the use of plant products for various health purposes, including immune enhancement. This review aims to summarize the existing literature on immune-boosting phytochemicals in Nigeria and their activities. Relevant and accurate literature were sourced from WHO. CDC, NCDC, PubMed, Scopus, PLoS One Crossref, Google Scholar, and NATURE Journals. Several studies have identified various phytochemicals with immunomodulatory properties from Nigerian medicinal plants, including alkaloids, flavonoids, terpenoids, phenolic compounds, and polysaccharides. These phytochemicals have been shown to exhibit diverse mechanisms of action, such as antioxidant, anti-inflammatory, antimicrobial, and immunostimulatory activities, which can potentially support the immune system and improve overall health. However, there are still knowledge gaps that need to be addressed in this field. Further research is needed to elucidate the molecular mechanisms underlying the immunomodulatory activities of these phytochemicals and their safety and efficacy in human subjects. To ensure consistency and reproducibility of results, it is crucial to standardize the methods used for extracting, isolating, and characterizing phytochemicals from Nigerian plant products. Quality control measures must also be put in place. Moreover, studies on the sustainable sourcing, cultivation, and conservation of medicinal plants in Nigeria are crucial to ensure their availability for future generations. Bridging these knowledge gaps will facilitate the development of evidence-based interventions using immune-boosting phytochemicals from Nigerian plant products for the management of immune-related health conditions. Further exploration of the immunomodulatory potential of Nigerian plant products and their phytochemicals has the potential to contribute to the development of novel strategies for enhancing immune function and improving overall health.
Published Version
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