Abstract
The Bombay and para-Bombay blood groups are rare blood types that are significant to clinical blood transfusions. Accurate para-Bombay blood group identification is important for the safety of transfusions. Serological and molecular biology methods were used to detect one case of ABO blood type. Genotypes of the para-Bombay blood group in the Chinese population were searched and summarized, and the safety of blood transfusion for this group was discussed. The ABO genotype of the case was B101/O01 and the FUT1 gene haplotype was c.649T and 881_882 delTT, while the phenotypes were Bmh, h2/h649, Le(a-b-), and Se357/Se357,716. The h649/h2 FUT1 genotype is newly discovered and is responsible for the para-Bombay blood group in the Chinese population. Accurate identification of this blood group using serology and molecular methods is significant to ensure the safety of blood transfusions.
Published Version
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