Iatrogenic allogenesis and autoimmune diseases

Abstract

Introduction. Iatrogenic allogenesis is currently a public health problem due to the constant increase in cases, especially in underdeveloped countries. Objective. To characterize patients diagnosed with iatrogenic allogenesis. Methods. An observational, descriptive, cross-sectional study was conducted in 23 patients with a confirmed diagnosis of iatrogenic allogenesis. Adverse reactions, the appearance of autoimmune diseases, and their association with the type of substance injected were described. Results. Women aged 30-39 years, single, and with non-university education predominated. 48% of patients received the infiltration by stylists in beauty salons. The most common infiltration area was the face, and 39% of patients did not know the substance that was injected. Granulomatous reactions, generalized pain, and nodule formation predominated, associated with all the molding agents used and with injections in the face. Contour changes and asymmetry were associated with the use of silicones and biopolymers and were more common with injections in the face and buttocks. 47.8% of patients were diagnosed with autoimmune diseases, with vasculitis and systemic lupus erythematosus being the most common. 63.6% of those diagnosed with autoimmune diseases were infiltrated with substances of unknown type. Conclusions. Granulomatous reactions, generalized pain, and nodule formation predominated, along with the diagnosis of vasculitis and systemic lupus erythematosus; these were more frequently associated with the injection of substances of unknown origin and composition