Abstract
Introduction The triangular neuronal circuit between the red nucleus, the ipsilateral inferior olivary nucleus and the contralateral dentate nucleus as part of the extrapyramidal motor system was first described by Guillain & Mollaret in 1931 [1]. It consists of fibers running in the central tegmental tract from the red nucleus to the ipsilateral inferior olivary nucleus, from here to the contralateral dentate nucleus through the inferior cerebellar peduncle and from there via the dentatorubral tract running in the superior cerebellar peduncle back to the ipsilateral red nucleus (Figure 1). This neuronal circuit acts as an inhibitory system on cortical generated impulses by comparing them with their performance in the peripheral motor effector organs. Lesions including parts of the Guillain-Mollaret triangle may result in a rare, but characteristic hypertrophic degeneration of the inferior olivary nucleus [2].
Published Version
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