Abstract
During physical activity, systemic response is dependable from interaction of training stimuli and adaptive systems such as musculoskeletal, cardiorespiratory and endocrine. Newer research also indicates that there is endocrine response of certain immune factors and also towards influence that immune response has on metabolic changes during physical activity. This further makes understanding more complex, but with purpose to provide full picture and illustrate the complexity of systemic functioning. From endocrine point of view, regarding as important homeostatic system especially with role towards stress and exercise response, one of hormones that has important role is catabolic hormone cortisol for which secretion adrenal gland is responsible. In this paper, and based on current evidence, focus is towards cortisol role in metabolism during physiologic conditions and as response of this hormone to stress caused by training stimulus.
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