Abstract

This chapter focuses on the membrane transport proteins that are the members of the H+/ oligopeptide symporter family. Transporters of this family mediate the uptake of oligopeptides, chlorate, and nitrate. Members of the family have a broad biological distribution that includes bacteria, plants, and humans. They are predicted to contain 11, 12, or 13 membrane-spanning helices by the hydropathy of their amino acid sequences. The chapter discusses the nomenclature, biological sources, substrates, phylogenetic trees, topology plot, physical and genetic characteristics, conserved motifs, multiple amino acid sequence alignments, and database accession numbers for members of the H+/ oligopeptide symporter family. Statistical analysis reveals no apparent relationship among the amino acid sequences of the H+/oligopeptide symporter family and any other family of transporters.

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