Abstract
Background: Various neoplastic and non-neoplastic diseases affect the eye and orbit. Different tissues of ocular area contribute to lesions that varies from inflammation to different types of neoplastic conditions. Histopathology is the key to diagnosis for most neoplastic and non-neoplastic swellings. Histopathological studies have the indirect role to ongoing patient care.
 Materials and Methods: It was a retrospective study of ocular biopsies done in Himalayan Eye Hospital Gharipatan, Pokhara. These biopsy specimens were submitted during the period of one year (2018/12/1 to 2019/12/1).
 Results: The total number of biopsies we analyzed for ocular lesions were 102. Maximum number of patients were from the second decade. Out of 102 cases, 7(6.86%) were neoplastic and 95(96.07%) were non neoplastic cases. Two cases of SCC were diagnosed out of 102 specimens, while one case each of non-Hodgkin’s lymphoma and meibomian gland carcinoma were detected.
 Conclusion: Epidermal cyst and nevus were the most common non-neoplastic lesions in this study. SCC and non-Hodgkin’s lymphoma were the commonest malignant lesions in the present study.
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