Spectrum of neoplastic and non neoplastic skin lesions: A histopathological institutional study

Abstract

Skin lesions are complex due to wide range of neoplastic and non-neoplastic lesions. Several studies showed high prevalence of skin disorders in developing countries. Clinical presentation is restricted to hyperpigmentation, hypopigmentation, macules, papules and nodules but histopathology is highly variable. Accurate diagnosis is needed due to disease specific treatment and prognosis. Aim of the study is to evaluate different histopathological patterns of skin lesions for accurate diagnosis and to analyze age and sex distribution of skin lesions.: The study included a total number of 125 skin biopsies from July 2018 to June 2019 sent for histopathological examination to pathology department, SVS Medical College, Mahabubnagar, Telangana, India. In our study total 125 cases were analyzed. Out of which majority of the lesions (38.97 %) were in the age group of 21-40 years. Present study showed cutaneous cysts being the most common non-neoplastic lesion. In malignant tumors, out of 20 cases, 50% cases were Squamous cell carcinoma followed by basal cell carcinoma (30%). Even though clinical features are few biopsy shows varied pathology and it is crucial for accurate diagnosis and differential diagnosis of skin lesions. Skin biopsy is a simple, inexpensive and gold standard method for definitive diagnosis and treatment of skin lesions. In the present study, n on neoplastic lesions are more common than neoplastic skin lesions. Non neoplastic lesions more common in younger males of 21-40 yrs and neoplastic lesions in older age group. Epidermal cyst is most common non neoplastic lesion followed by trichilemmal cyst. Squamous papilloma is the most common benign neoplasm & Squamous cell carcinoma is the most common malignant neoplasm.