Abstract
The purpose of the work is to study the features of histomorphometric changes in the pancreas of rats under conditions of hyperosmolar dehydration.Material and methods. The experiment was conducted on 40 adult white malerats. The control series of animals was 10 rats, the experimental series was divided depending on the degree of dehydration into 3 groups of 10 rats each.Results. Under conditions of hyperosmolar dehydration, we found the following statistically significant changes. An increase in acinus area was observed with mild dehydration and amounted to 39.9%; pancreatic islets – with moderate and severe degrees of 51,6 % and 45.9 %. The area of exocrine pancreatocytes decreased with moderate and severe degrees by 29,6 % and 35,9 %, with an increase in the area of their nuclei by 46,2 % under conditions of severe dehydration.Conclusions. Changes in the parenchyma of the pancreas and microvasculature progress in direct proportion to the increase in the severity of dehydration.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
