Abstract

Myocardial infarction (MI) remains a leading cause of mortality and morbidity, while percutaneous coronary intervention (PCI) has become the most commonly performed invasive therapeutic procedure among patients with cardiovascular disease 1 . Aspirin, a non-selective cycloxegenase inhibitor, and clopidogrel, a platelet P2Y12 receptor inhibitor, are universally administered to patients undergoing a percutaneous revascularization because of their proven efficacy in reducing major adverse cardiovascular events, making them one of the most frequently prescribed drugs worldwide. Despite clear improvements in platelet-directed therapy, thrombotic events remain common, both early and late after PCI with or without a stent implantation 2,3

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