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https://doi.org/10.1021/ja054549f
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Cite Publication Date: Aug 31, 2005 | |
 Citations: 1411 |
Affiliation: University of Houston
A new palladium-catalyzed arylation process based on C-H activation has been developed. The utilization of pyridine-containing directing groups allows the beta-arylation of carboxylic acid derivatives and gamma-arylation of amine derivatives. Both primary and secondary sp3 C-H bonds, as well as sp2 C-H bonds, are reactive.
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