Abstract
AMSBIO’s new 3D Culture 96-Well Basement Membrane Extract (BME) Cell Invasion Assay offers a flexible, standardized, high-throughput format for quantitating the degree to which invasive cells in 3D spheroid cultures penetrate a barrier consisting of basement membrane components in response to chemo attractants and/or inhibiting compounds. The new 3D Culture 96 Well BME Cell Invasion Assay uses a 3D Culture Qualified 96-Well Spheroid Formation Plate alongside a specialized Spheroid Formation extracellular matrix to drive aggregation and/or spheroid formation of cells. Upon completion of spheroid formation, the spheroid is embedded in an invasion matrix composed of basement membrane proteins. This matrix forms a hydrogel network on which invasive cells can travel. At this point, invasion-modulating agents can be applied to the system to evaluate the impact on cell response. Cell invasion is visualized microscopically and can be quantitated through image analysis software. More: www.amsbio.com/3D-CultureSpheroid-Cell-Invasion-Assay.aspx Cell Adhesion Assays
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