Abstract
Abstract 1. 1. Hepatic microsomal UDP glucuronyl transferase activity towards 4,5,6-trichloroguaiacol was characterized in five species of fish. The simple extraction technique used to determine glucuronidation rates was sufficiently accurate, as judged by high pressure liquid chromatography. 2. 2. UDP glucuronyl transferase activities were found to vary considerably between fish species. The level of UDP glucuronyl transferase activity in rainbow trout is among the highest in vitro conjugating activities reported in fish. 3. 3. Intraperitoneal injection of β-naphthoflavone resulted in an almost doubling of the UDP glucuronyl transferase activity in rainbow trout.
Published Version
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