Henoçh-Schönlein Vaskülitli Olguların Değerlendirilmesi

Abstract

Analysis of The Cases With Henoch-Schonlein Vasculitis Henoch-Schonlein vasculitis is the most common systemic vasculitis in children and it has a benign course and characterized purpura, arthritis and gastrointestinal and/or renal involvement. In this study we planned to analyze and compare of the clinical and laboratory characteristics of the patient with Henoch-Schonlein vasculitis with literature. We analyzed 135 cases with Henoch-Schonlein vasculitis, who.had been followed up at the departments of pediatrics of Ondokuz Mayis University and Gulhane Military Medical School between January 1993 and January 2000. retrospectively. Of the 135 patients, eighty (59.2%) were male and fifty-five (40.8%) were girl, and the median age was 9.5 years (10 months to 17 years). The distribution of the patients to Die season was as follows: 15% in spring. 18.5% in summer, 21.1% in autumn, and 45.4% in winter. The most complaints of admission were purpura (100%). abdominal pain (62%) and arthralgia (48.8%). There was a positive history of upper respiratory tract infection in the last month in 4.1.4% of the cases. On physical examination, purpura, arthritis, edema of the legs, fever and hypertension were, found in the 100%. 37.7%, 3-1.8%, 1 1%) and 5.9% of the cases, respectively. Gastrointestinal hemorrhage, renal involvement, and scrotal involvement were observed 29.6%, 55.5% and 7,4% of the cases, respectively. II was learned that one patient had been appendect.om.teed a month before. While the improvement lime has not been different between the cases with or without complication, microscopic hematuria continued 2 to 6 months in the patients who had renal involvement. Henoch-Schonlein purpura has a benign course and permanent complications resulted from organ involvement are very rare. Henoch-Schonlein vaskuliti, cocuklarda en sik gorulen sistemik vaskulit olup purpura. arlriL ve gastrointestinal ve/veya bobrek tutulumu ile karakterize selim seyirli bir hastaliktir. Bu calismada Henoch-Schonlein vaskuliti tanisi alan hastalarimizin klinik ve laboratuar bulgularini inceleyerek literatur bilgisi ile karsilastirilmasi planlandi. Bu cali-niada Ocak 1993 ile Ocak 2000 tarihleri arasinda Ondokuz Mayis Universitesi ve Gulhane Askeri Tip Akademisi Pediatri Anabilim Dallarinda Henoch-Schonlein vaskuliti tanisi almis 135 hasta retrospektif olarak gozden gecirildi. Hastalarin 80'i (%59.2) erkek. 55'i (%40.8) kiz olup, medyan yas 9.5 idi (10 ay - 17 yas arasi). Olgularin mevsimlere gore dagilimi: Ilkbahar %15, yaz %18.5. sonbahar %2 1.1 ve %45.4 kis. En sik basvuru sikayetleri dokuntu (%100), karin agrisi (%62) ve eklem agrisi (%48.8) idi. Fizik muayenede purpura, artrit, ayaklarda odem, ates ve hipertansiyon sirasiyla %100, %37.7, %31.8, %1 1 ve %5.9 oraninda bulundu. Hastalarin seyrinde gastrointestinal kanama, renal tutulum ve skrotal tutulum sirasiyla %29.6, %55.5 ve %7.4 oranlarinda saptandi. Bir hastanin bir ay once apendektomi gecirdigi ogrenildi. Organ tutulumu olan ve olmayan hastalarda iyilesme zamani farklilik gostermezken, renal tutulumu olan hastalarda mikroskobik hematini 2 ile 6 ay devam etli. Henoch-Schonlein vaskuliti selim seyiiii bir hastalik olup organ tutulumu sonucu kalici komplikasyonlar cok nadirdir.