Abstract
Context: Irrigation is a critical component in accessing the labyrinth of the pulp space. Although traditional irrigants such as sodium hypochlorite (NaOCl) are widely employed, they exhibit several limitations, including cytotoxicity and complete microbial eradication. In contrast, phytochemicals derived from plants, including coffee, present promising alternatives due to their established antimicrobial properties. Aims: The aim of this study was to evaluate the efficacy of intracanal irrigants derived from locally cultivated Coffea arabica and Coffea canephora (Robusta) varieties, both recognized for their antimicrobial attributes. Subjects and Methods: A total of 70 extracted human single-rooted teeth were prepared. Coffee extracts were prepared through a decoction method, and the minimum inhibitory concentrations (MICs) of these extracts were determined using microbroth dilution assays. Microbial growth was quantitatively assessed at predetermined intervals. Results: Green Robusta extracts exhibited antimicrobial effectiveness at lower concentrations of 25% and 12.5%. All coffee extract groups demonstrated substantial reductions in microbial counts compared to the negative control, with Robusta extracts proving particularly efficacious. Notably, the Robusta green 12.5% extract exhibited sustained antimicrobial efficacy, suggesting its potential as an alternative to NaOCl. Conclusions: The findings of this study suggest a novel approach to improving endodontic therapy outcomes through the utilization of coffee extracts, potentially enhancing dental health.
Published Version
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