Abstract

Protection against radiation by preradiation measures for a wide spectrum of living things is now an accomplished fact. The administration of sulfhydryl compounds and the induction of severe hypoxia seem to be the most effective means of reducing the effectiveness of radiation. Chemcial protection against ionizing radiation can be done by (1) protection by cysteine and glutathione and (2) chronological development of information about sulfhydryl protection. The chapter also explains the experiments to investigate comparative effects of para-aminopropio-phenone (PAPP) and glutathione (GSH) as protective agents against radiation injury. It also discusses the experiments designed to investigate primary destruction and regenerative ability in nontreated and glutathione-pretreated mice.

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