Global dynamics of an SIS compartment model with resource constraints.

Abstract

This paper formulates a mathematical framework to describe the dynamics of SIS-type infectious diseases with resource constraints. We first define the basic reproduction number that determines disease prevalence and analyze the existence and local stability of the equilibria. Subsequently, we analyze the global dynamics of the model, excluding periodic solutions and heteroclinic orbits, using the compound matrix approach. The analysis implies that the model can undergo forward and backward bifurcations depending on critical parameters. In the former scenario, the disease persists when the basic reproduction number under resource constraints exceeds one. In the latter scenario, the backward bifurcation creates bistability dynamics in which the disease may persist or become extinct depending on the initial level of infected individuals and the resource abundance.