Abstract
Тhis review is based on literature data analysis on genetic markers associated with vitamin E metabolism. We focus on the SNPs associated with different pathologic conditions: a decrease of active form of vitamin E in serum. Also reviewed the current recommendations on nutrition and drug treatment of hypovitaminosis.
Highlights
Federal State Budgetary Institution of Science Institute of chemical biology and fundamental medicine, Siberian branch of the Russian Academy of Sciences (ICBFM SB RAS), Novosibirsk, Russia
Тhis review is based on literature data analysis on genetic markers associated with vitamin E metabolism
We focus on the SNPs associated with different pathologic conditions: a decrease of active form of vitamin E in serum
Summary
Генетические предпосылки снижения концентрации токоферола в сыворотке крови Зеленская Е. И. Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН), Новосибирск, Россия. Проведён анализ данных литературы по генетическим маркерам, ассоциированным со снижением активной формы витамина Е в сыворотке крови. Также рассмотрены современные рекомендации по питанию и медикаментозному лечению гиповитаминоза Е. Ключевые слова: витамин Е; α-TTP; СYP4F2; ZNF259; SCARB1; токоферол; токотриенол. И. Генетические предпосылки снижения концентрации токоферола в сыворотке крови. Genetic prerequisites for reducing serum tocopherol concentration Zelenskaya EM, Lifshits GI. Federal State Budgetary Institution of Science Institute of chemical biology and fundamental medicine, Siberian branch of the Russian Academy of Sciences (ICBFM SB RAS), Novosibirsk, Russia
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