Abstract
The objective of the investigation was to characterize infectious bursal disease viruses (IBDV) circulating in commercial poultry farms in Ukraine between 2014 and 2016. IBDV genetic material was amplified directly from bursa. The nucleotide sequence for VP2 hypervariable region of 16 IBDVs were determined by RT-PCR method, sequenced and compared to well characterised IBDV isolates worldwide. Neighbor-joining method was used for phylogenetic analyses. In result of the studyUkrainian IBDVs represented two genetic lineages: very virulent (vv) IBDVs and classical IBDV closely related to attenuated vaccine stains. The nucleotide identity among UkrainianvvIBDVs ranged between 87.2% and 99,8%. Ukrainian vvIBDV strains clustered together with very virulent strains from other counties like: United Kingdom, Egypt, China, Netherlands and Spain. In conclusion this report demonstrates the circulation of vvIBDV in commercial poultry farms in Ukraine.
Highlights
Herpes simplex virus type 1 (HSV-1) is member of the Alphaherpesvirinae subfamily within the Herpesviridae virus family [1]
HSV-1 is a common infection in developed countries where rates of seropositivity usually exceed 50%
Infectious virus is eventually cleared, a latent infection is established in neurons of the peripheral nervous system (PNS) ganglia [1,2]
Summary
Herpes simplex virus type 1 (HSV-1) is member of the Alphaherpesvirinae subfamily within the Herpesviridae virus family [1]. HSV-1 is a common infection in developed countries where rates of seropositivity usually exceed 50% In both humans and experimental animals, primary infection of skin or mucosa results in the local replication of virus, infection of sensory nerve ending, and spread via retrograde axonal transport to the ganglia of the peripheral nervous system (PNS) where a productive infection of neurons ensues. Serotype 1 IBDVisolates comprise the variant, classical virulent (cvIBDV) and very virulent (vvIBDV) strains, which greatlydiffer in their pathogenicity to chickens.VvIBDV strains were detected in Europe in 1986 and caused 70% mortality in susceptible chickens. These strains still cause great economical impact in poultry industry worldwide [3]. VvIBDV strains have been characterized in many countries, but there were no publications about these strains in Ukraine
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call