Abstract
Publisher Summary This chapter presents a general orientation of human lymphocyte subpopulations. Study of subpopulations of lymphocytes in man is now a highly developed field. Surface markers including receptors for complement components, receptors for several different immunoglobulins, differentiation antigens recognized by heteroantisera and monoclonal anti-bodies prepared by the hybridoma technologies, and also receptors for surface components of certain red blood cell antigens, and enzymes and lectins from a variety of sources have all been used to recognize and define lymphocyte subpopulations. The understanding of primary and secondary immunodeficiencies, the definition and analysis of lymphoreticular malignancies, the investigation of autoimmunities, and the understanding of the influences of persisting infections and modern chemotherapy and consequences of malignant diseases require the application of these techniques.
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