Abstract
This present work is aimed at determining the chemical components in Senna alata (L.) Roxb. (Fabales: Fabaceae), that contains a large array of phenolic compounds which make it useful as antifungal and antibacterial. Despite a notable success in the recent researches, yet, the quantification of the chemical components has not been actually specified. There is a claim by local people that S. alata can cure fungi and bacteria related diseases. Therefore, there is a need to ascertain this claim by examining the bioactive components present in the plant. The Gas Chromatography (GC) analysis was performed using a Clarus 500 Perkin Elmer gas chromatography equipped with an Elite-5 capillary column with the addition of an absolute alcohol. The antimicrobial analysis was carried out using Agar Disc Diffusion Method. In the GC chromatogram, four prominent peaks were observed in leaf chromatogram, three peaks in flower chromatogram and five peaks in fruit chromatogram, respectively. The flower contained the highest amount of cinnamic acid (52.91%) and the fruit contained the least (17.03%). The presence of some bioactive metabolites could be responsible for the observed antifungal and antibacterial activities on the susceptible organisms studied. It could be concluded that this plant is natural sources of antimicrobial substances of high importance and are useful in chemotherapy.
Highlights
IntroductionSenna alata (L.) Roxb. (Fabales: Fabaceae) (previously named Cassia alata) is a medicinal plant of Fabaceae Family
Senna alata (L.) Roxb. (Fabales: Fabaceae) is a medicinal plant of Fabaceae Family
The fractions of S. alata obtained were analyzed on a pre-coated silica gel plate in order to identify the compounds present in each of the fractions obtained from the extracts
Summary
Senna alata (L.) Roxb. (Fabales: Fabaceae) (previously named Cassia alata) is a medicinal plant of Fabaceae Family. (Fabales: Fabaceae) (previously named Cassia alata) is a medicinal plant of Fabaceae Family. It has many common names such as candle bush, acapulo, ringworm bush and calabra bush. It is a shrub with usually an average height of between 1 and 5 m and has horizontally spread branches. S. alata are able to synthesize a multitude of organic molecules or phytochemicals, referred to as “secondary metabolites” such as phenolic compounds (Shahidi et al, 2004). Phenolic compounds are plant secondary metabolites that constitute one of the most common and widespread groups of substances in plants
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